BDBM50198352 1-(5-acetyl-6,6'-dihydroxy-2',3'-dihydro-[2,3']-bibenzofuranyl-5'-yl)-ethanone::CHEMBL224735

SMILES CC(=O)c1ccc2oc(cc2c1O)-c1coc2ccc(C(C)=O)c(O)c12

InChI Key InChIKey=OOMZWMYSDVPPNA-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50198352   

TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50198352(1-(5-acetyl-6,6'-dihydroxy-2',3'-dihydro-[2,3']-bi...)
Affinity DataKi:  2.75E+4nMAssay Description:Inhibition of PTP1B in presence of 0.01% Triton X-100More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50198352(1-(5-acetyl-6,6'-dihydroxy-2',3'-dihydro-[2,3']-bi...)
Affinity DataKi:  3.50E+4nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50198352(1-(5-acetyl-6,6'-dihydroxy-2',3'-dihydro-[2,3']-bi...)
Affinity DataIC50:  8.70E+4nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50198352(1-(5-acetyl-6,6'-dihydroxy-2',3'-dihydro-[2,3']-bi...)
Affinity DataIC50:  5.88E+4nMAssay Description:Inhibition of PTP1B in presence of 0.01% Triton X-100More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed