BDBM50199598 4-(4-(difluoromethoxy)phenyl)-7-(3-(4-fluoropiperidin-1-yl)propoxy)-2-methyl-1,2,3,4-tetrahydroisoquinoline::CHEMBL246954

SMILES CN1CC(c2ccc(OC(F)F)cc2)c2ccc(OCCCN3CCC(F)CC3)cc2C1

InChI Key InChIKey=LGUCWRBFHWJFMF-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50199598   

TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50199598(4-(4-(difluoromethoxy)phenyl)-7-(3-(4-fluoropiperi...)
Affinity DataKi:  3nMAssay Description:Binding affinity at rat SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50199598(4-(4-(difluoromethoxy)phenyl)-7-(3-(4-fluoropiperi...)
Affinity DataKi:  4.30nMAssay Description:Binding affinity at human SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50199598(4-(4-(difluoromethoxy)phenyl)-7-(3-(4-fluoropiperi...)
Affinity DataKi:  10nMAssay Description:Binding affinity at human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed