BDBM50200734 (R)-1-((R)-2-acetamidopropanoyl)pyrrolidin-2-ylboronic acid::CHEMBL387462

SMILES C[C@@H](NC(C)=O)C(=O)N1CCC[C@H]1B(O)O

InChI Key InChIKey=METFGSCNIQTFJC-SVRRBLITSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50200734   

TargetProlyl endopeptidase FAP(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50200734((R)-1-((R)-2-acetamidopropanoyl)pyrrolidin-2-ylbor...)
Affinity DataKi:  350nMAssay Description:Inhibitiory constant against FAPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl endopeptidase(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50200734((R)-1-((R)-2-acetamidopropanoyl)pyrrolidin-2-ylbor...)
Affinity DataKi:  2.71E+3nMAssay Description:Inhibitory constant against POPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl endopeptidase(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50200734((R)-1-((R)-2-acetamidopropanoyl)pyrrolidin-2-ylbor...)
Affinity DataIC50:  130nMAssay Description:Inhibition of human PREP using Z-Gly-Pro-AMC as substrate preincubated for 10 mins prior to substrate addition by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl endopeptidase FAP(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50200734((R)-1-((R)-2-acetamidopropanoyl)pyrrolidin-2-ylbor...)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of human FAP using Z-Gly-Pro-AMC as substrate preincubated for 10 mins prior to substrate addition by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed