BDBM50200778 CHEMBL3926060

SMILES C[C@@H]1CN(Cc2ccc(o2)C(F)(F)F)c2cnccc2[C@H](C)N1C(=O)NCc1ccccc1

InChI Key InChIKey=YHHLMYMWSPRPHL-SJORKVTESA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50200778   

TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50200778(CHEMBL3926060)
Affinity DataIC50:  37nMAssay Description:Channel blocking activity at recombinant human CaV 3.1 channel expressed in HEK293 cells assessed as inhibition of Ca2+ flux preincubated for 3 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50200778(CHEMBL3926060)
Affinity DataIC50:  44nMAssay Description:Channel blocking activity at recombinant human CaV 3.2 channel expressed in HEK293 cells assessed as inhibition of Ca2+ flux preincubated for 3 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1I(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50200778(CHEMBL3926060)
Affinity DataIC50:  10nMAssay Description:Channel blocking activity at recombinant human CaV 3.3 channel expressed in HEK293 cells assessed as inhibition of Ca2+ flux preincubated for 3 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed