BDBM50201064 (1R,6S)-2-bromo-5-(3,8-diaza-bicyclo[4.2.0]oct-3-yl)-nicotinonitrile::5-((1R,6S)-3,8-diaza-bicyclo[4.2.0]octan-3-yl)-2-bromonicotinonitrile::CHEMBL374692

SMILES Brc1ncc(cc1C#N)N1CC[C@H]2CN[C@H]2C1

InChI Key InChIKey=LDWPOKRYKSONRV-KWQFWETISA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50201064   

TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50201064((1R,6S)-2-bromo-5-(3,8-diaza-bicyclo[4.2.0]oct-3-y...)
Affinity DataEC50:  6.10nMAssay Description:Agonist activity at human alpha4beta2 ACHR expressed in HEK293 cells assessed as change in intracellular calcium concentration by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Homo sapiens (Human))
Burnham Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50201064((1R,6S)-2-bromo-5-(3,8-diaza-bicyclo[4.2.0]oct-3-y...)
Affinity DataEC50:  4.37nMAssay Description:Agonist activity against human alpha3beta4 nAChRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
Burnham Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50201064((1R,6S)-2-bromo-5-(3,8-diaza-bicyclo[4.2.0]oct-3-y...)
Affinity DataEC50:  6.17nMAssay Description:Agonist activity against human alpha4beta2 nAChRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed