BDBM50201342 CHEMBL394203::N-(3,5-bis(trifluoromethyl)phenyl)-1-methyl-4-(pyridin-4-ylmethylamino)-1H-imidazole-5-carboxamide

SMILES Cn1cnc(NCc2ccncc2)c1C(=O)Nc1cc(cc(c1)C(F)(F)F)C(F)(F)F

InChI Key InChIKey=RVGGSPYQXPOZQH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50201342   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chemical Diversity

Curated by ChEMBL
LigandPNGBDBM50201342(CHEMBL394203 | N-(3,5-bis(trifluoromethyl)phenyl)-...)
Affinity DataIC50:  1.06E+3nMAssay Description:Inhibition of VEGFR2 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chemical Diversity

Curated by ChEMBL
LigandPNGBDBM50201342(CHEMBL394203 | N-(3,5-bis(trifluoromethyl)phenyl)-...)
Affinity DataIC50:  150nMAssay Description:Inhibition of VEGFR2 by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Chemical Diversity

Curated by ChEMBL
LigandPNGBDBM50201342(CHEMBL394203 | N-(3,5-bis(trifluoromethyl)phenyl)-...)
Affinity DataIC50:  740nMAssay Description:Inhibition of VEGFR1 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed