BDBM50201711 CHEMBL3951922::US9775839, 2.2

SMILES C[C@H](N)CNc1cnc(C(N)=O)c(n1)-c1cc2ccccc2[nH]1

InChI Key InChIKey=NYYIGJQYEWZYJP-VIFPVBQESA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50201711   

TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50201711(CHEMBL3951922 | US9775839, 2.2)
Affinity DataIC50:  5.20nMAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50201711(CHEMBL3951922 | US9775839, 2.2)
Affinity DataIC50:  5nMAssay Description:Inhibition of GST-tagged full length human SYK (1 to 635 end residues) expressed in baculovirus expression system preincubated for 10 mins followed b...More data for this Ligand-Target Pair