BDBM50201782 1-(3,4-dichlorophenyl)-3-(dimethylamino)propan-1-one hydrochloride::CHEMBL264166::CHEMBL536752

SMILES CN(C)CCC(=O)c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=LZXMNZWXKWSYMY-UHFFFAOYSA-N

Data  1 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50201782   

TargetSortase family protein(Staphylococcus aureus)
University Of Chicago

Curated by ChEMBL
LigandPNGBDBM50201782(1-(3,4-dichlorophenyl)-3-(dimethylamino)propan-1-o...)
Affinity DataKi:  1.57E+4nMAssay Description:Inhibition of Staphylococcus aureus sortase AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma brucei brucei)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50201782(1-(3,4-dichlorophenyl)-3-(dimethylamino)propan-1-o...)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of TR by DTNB-coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutathione reductase, mitochondrial(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50201782(1-(3,4-dichlorophenyl)-3-(dimethylamino)propan-1-o...)
Affinity DataIC50:  6.48E+4nMAssay Description:Inhibition of human GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSortase family protein(Staphylococcus aureus)
University Of Chicago

Curated by ChEMBL
LigandPNGBDBM50201782(1-(3,4-dichlorophenyl)-3-(dimethylamino)propan-1-o...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of human rhodamine-labelled soluble CD69 by standard plate inhibition assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSortase family protein(Staphylococcus aureus)
University Of Chicago

Curated by ChEMBL
LigandPNGBDBM50201782(1-(3,4-dichlorophenyl)-3-(dimethylamino)propan-1-o...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of 6-His tagged Staphylococcus aureus recombinant sortase delta N24 expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSortase family protein(Staphylococcus aureus)
University Of Chicago

Curated by ChEMBL
LigandPNGBDBM50201782(1-(3,4-dichlorophenyl)-3-(dimethylamino)propan-1-o...)
Affinity DataIC50:  1.69E+4nMAssay Description:Inhibition of Staphylococcus aureus sortase A using dabcyl-QALPETGEE-edans as substrate incubated for 1 hr prior to substrate addition measured at 1 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSortase family protein(Staphylococcus aureus)
University Of Chicago

Curated by ChEMBL
LigandPNGBDBM50201782(1-(3,4-dichlorophenyl)-3-(dimethylamino)propan-1-o...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of Staphylococcus aureus sortase AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed