BDBM50202437 CHEMBL502013

SMILES OC(=O)c1cccc(N\N=C2/C(=O)Nc3ccc(cc23)S(=O)(=O)NCc2ccc(F)cc2)c1

InChI Key InChIKey=ABVSYWGFUNXYAC-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50202437   

TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Egyptian Russian University

Curated by ChEMBL
LigandPNGBDBM50202437(CHEMBL502013)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of GST-tagged Shp2 PTP domain (unknown origin) using DiFMUP as substrate measured after 5 to 10 mins by fluorescence analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Egyptian Russian University

Curated by ChEMBL
LigandPNGBDBM50202437(CHEMBL502013)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of SHP2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50202437(CHEMBL502013)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of PTP1B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50202437(CHEMBL502013)
Affinity DataIC50:  18nMAssay Description:Inhibition of SHP1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Egyptian Russian University

Curated by ChEMBL
LigandPNGBDBM50202437(CHEMBL502013)
Affinity DataIC50:  1nMAssay Description:Inhibition of SHP2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed