BDBM50202737 CHEMBL395665::N-(4-(4-amino-7-(3-((1r,4r)-4-aminocyclohexylamino)prop-1-enyl)thieno[3,2-c]pyridin-3-yl)-2-methoxyphenyl)-1-methyl-1H-indole-2-carboxamide

SMILES COc1cc(ccc1NC(=O)c1cc2ccccc2n1C)-c1csc2c(\C=C\CN[C@H]3CC[C@H](N)CC3)cnc(N)c12

InChI Key InChIKey=FRQGIFZNGIECRT-LSKJDRFGSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50202737   

TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50202737(CHEMBL395665 | N-(4-(4-amino-7-(3-((1r,4r)-4-amino...)
Affinity DataIC50:  1.97E+4nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Fgr(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50202737(CHEMBL395665 | N-(4-(4-amino-7-(3-((1r,4r)-4-amino...)
Affinity DataIC50:  1.79E+4nMAssay Description:Inhibition of FgrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lyn(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50202737(CHEMBL395665 | N-(4-(4-amino-7-(3-((1r,4r)-4-amino...)
Affinity DataIC50:  1.85E+4nMAssay Description:Inhibition of LynMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50202737(CHEMBL395665 | N-(4-(4-amino-7-(3-((1r,4r)-4-amino...)
Affinity DataIC50:  2.59E+4nMAssay Description:Inhibition of FynMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50202737(CHEMBL395665 | N-(4-(4-amino-7-(3-((1r,4r)-4-amino...)
Affinity DataIC50:  1.85E+4nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50202737(CHEMBL395665 | N-(4-(4-amino-7-(3-((1r,4r)-4-amino...)
Affinity DataIC50:  110nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase HCK(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50202737(CHEMBL395665 | N-(4-(4-amino-7-(3-((1r,4r)-4-amino...)
Affinity DataIC50:  2.41E+4nMAssay Description:Inhibition of HckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50202737(CHEMBL395665 | N-(4-(4-amino-7-(3-((1r,4r)-4-amino...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed