BDBM50202739 CHEMBL395664::N-(4-(4-amino-7-(3-(piperidin-4-ylamino)prop-1-enyl)thieno[3,2-c]pyridin-3-yl)-2-methoxyphenyl)-1-methyl-1H-indole-2-carboxamide

SMILES COc1cc(ccc1NC(=O)c1cc2ccccc2n1C)-c1csc2c(\C=C\CNC3CCNCC3)cnc(N)c12

InChI Key InChIKey=DAQLGBCGVAJYAG-FNORWQNLSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50202739   

TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50202739(CHEMBL395664 | N-(4-(4-amino-7-(3-(piperidin-4-yla...)
Affinity DataIC50:  3.70E+3nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase HCK(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50202739(CHEMBL395664 | N-(4-(4-amino-7-(3-(piperidin-4-yla...)
Affinity DataIC50:  2.42E+4nMAssay Description:Inhibition of HckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lyn(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50202739(CHEMBL395664 | N-(4-(4-amino-7-(3-(piperidin-4-yla...)
Affinity DataIC50:  3.70E+3nMAssay Description:Inhibition of LynMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50202739(CHEMBL395664 | N-(4-(4-amino-7-(3-(piperidin-4-yla...)
Affinity DataIC50:  2.62E+4nMAssay Description:Inhibition of FynMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50202739(CHEMBL395664 | N-(4-(4-amino-7-(3-(piperidin-4-yla...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50202739(CHEMBL395664 | N-(4-(4-amino-7-(3-(piperidin-4-yla...)
Affinity DataIC50:  190nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50202739(CHEMBL395664 | N-(4-(4-amino-7-(3-(piperidin-4-yla...)
Affinity DataIC50:  1.44E+4nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Fgr(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50202739(CHEMBL395664 | N-(4-(4-amino-7-(3-(piperidin-4-yla...)
Affinity DataIC50:  2.65E+4nMAssay Description:Inhibition of FgrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed