BDBM50203263 CHEMBL3927265

SMILES Nc1n[nH]c2Oc3[nH]nc(N)c3C(c12)c1ccc(F)c(Cl)c1

InChI Key InChIKey=UYZFCOLDZJOODH-UHFFFAOYSA-N

Data  1 KI  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50203263   

TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Indian Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50203263(CHEMBL3927265)
Affinity DataKi:  107nMAssay Description:Inhibition of N-terminus 6xHis-tagged human IDO1 expressed in Escherichia coli M15 using L-tryptophan as substrate preincubated for 1 hr measured aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Indian Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50203263(CHEMBL3927265)
Affinity DataEC50:  139nMAssay Description:Inhibition of IDO1 in IFNgamma-induced human MDA-MB-231 cells using tryptophan as substrate preincubated for 4 hrs followed by substrate addition for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Indian Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50203263(CHEMBL3927265)
Affinity DataIC50:  78nMAssay Description:Inhibition of N-terminus 6xHis-tagged human IDO1 expressed in Escherichia coli M15 using L-tryptophan as substrate preincubated for 1 hr measured aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Indian Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50203263(CHEMBL3927265)
Affinity DataIC50:  378nMAssay Description:Inhibition of N-terminus 6xHis-tagged human IDO1 expressed in Escherichia coli M15 using L-tryptophan as substrate preincubated for 1 hr measured aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
Indian Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50203263(CHEMBL3927265)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of N-terminal 6xHis-tagged human TDO expressed in Escherichia cli Rosetta (DE3) pLysS using L-tryptophan as substrate preincubated for 1 h...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed