BDBM50203279 CHEMBL3940383
SMILES Cc1n[nH]c2Oc3[nH]nc(C)c3C(c12)c1ccc(F)c(F)c1
InChI Key InChIKey=JKOZOBNKGCZYHT-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50203279
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Indian Institute Of Technology
Curated by ChEMBL
Indian Institute Of Technology
Curated by ChEMBL
Affinity DataKi: 162nMAssay Description:Inhibition of N-terminus 6xHis-tagged human IDO1 expressed in Escherichia coli M15 using L-tryptophan as substrate preincubated for 1 hr measured aft...More data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Indian Institute Of Technology
Curated by ChEMBL
Indian Institute Of Technology
Curated by ChEMBL
Affinity DataEC50: 71nMAssay Description:Inhibition of IDO1 in IFNgamma-induced human MDA-MB-231 cells using tryptophan as substrate preincubated for 4 hrs followed by substrate addition for...More data for this Ligand-Target Pair
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
Indian Institute Of Technology
Curated by ChEMBL
Indian Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of N-terminal 6xHis-tagged human TDO expressed in Escherichia cli Rosetta (DE3) pLysS using L-tryptophan as substrate preincubated for 1 h...More data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Indian Institute Of Technology
Curated by ChEMBL
Indian Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 78nMAssay Description:Inhibition of N-terminus 6xHis-tagged human IDO1 expressed in Escherichia coli M15 using L-tryptophan as substrate preincubated for 1 hr measured aft...More data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Indian Institute Of Technology
Curated by ChEMBL
Indian Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 441nMAssay Description:Inhibition of N-terminus 6xHis-tagged human IDO1 expressed in Escherichia coli M15 using L-tryptophan as substrate preincubated for 1 hr measured aft...More data for this Ligand-Target Pair