BDBM50203652 CHEMBL3909872
SMILES Cc1cc(cc(C)c1OCCCC(O)=O)-c1cc(OC(F)(F)F)ccc1Cl
InChI Key InChIKey=KRJOUGOTSWPYDG-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 14 hits for monomerid = 50203652
Affinity DataIC50: 9.13E+3nMAssay Description:Inhibition of Nav1.5 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3.28E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck
Curated by ChEMBL
Merck
Curated by ChEMBL
Affinity DataIC50: 5.46E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
Affinity DataEC50: >9.95E+3nMAssay Description:Agonist activity at human GPR40 measured after 60 mins by IP1-HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 94nMAssay Description:Agonist activity at human GPR120 expressed in CHOK1 cells measured after 60 mins by IP1-HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 94nMAssay Description:Agonist activity at human GPR120 assessed as induction of IP1 accumulationMore data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 16nMAssay Description:Agonist activity at mouse GPR120 expressed in CHOK1 cells measured after 60 mins by IP1-HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 94nMAssay Description:Agonist activity at human GPR120 assessed as induction of IP1 accumulationMore data for this Ligand-Target Pair
Affinity DataEC50: 35nMAssay Description:Agonist activity at mouse GPR120 assessed as induction of IP1 accumulationMore data for this Ligand-Target Pair
Affinity DataEC50: 1.10E+3nMAssay Description:Agonist activity at human GPR120 assessed as induction of beta-arrestin recruitmentMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human GPR40 expressed in HEK293 cells assessed as induction of IP1 accumulation after 60 mins by HTRF assayMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Homo sapiens (Human))
Merck
Curated by ChEMBL
Merck
Curated by ChEMBL
Affinity DataIC50: 1.28E+4nMAssay Description:Inhibition of Cav1.2 (unknown origin)More data for this Ligand-Target Pair