BDBM50203945 (S)-N-(2,3-dimethylbenzyl)-N-(tetrahydro-2H-pyran-4-yl)pyrrolidin-3-amine::CHEMBL247733
SMILES Cc1cccc(CN([C@H]2CCNC2)C2CCOCC2)c1C
InChI Key InChIKey=BGSBHLAICAANSC-SFHVURJKSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 14 hits for monomerid = 50203945
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataKi: >7.50E+3nMAssay Description:Binding affinity to human ERGMore data for this Ligand-Target Pair
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of human CYP2D6More data for this Ligand-Target Pair
Affinity DataIC50: 727nMAssay Description:Inhibition of [3H]DA from human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of [3H]5HT from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 727nMAssay Description:Inhibition of [3H]DA reuptake at human dopamine transporter expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of [3H]5HT reuptake at human serotonin transporter expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of [3H]5-HT uptake at human recombinant 5HT transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of [3H]5HT uptake at human 5HT transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of [3H]NA uptake at human NA transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 727nMAssay Description:Inhibition of [3H]dopamine uptake at human dopamine transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of [3H]NA uptake at human recombinant NA transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 727nMAssay Description:Inhibition of [3H]DA uptake at human recombinant DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of [3H]NA from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of [3H]NA reuptake in human noradrenaline transporter expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair