BDBM50204276 CHEMBL3900985

SMILES [H][C@]12CO[C@H](CN1CCN(C2)C(=O)Cc1ccc(nn1)-n1cnnn1)c1ccc(F)c(C#N)c1C

InChI Key InChIKey=YPAKREDNTQZBQZ-OXJNMPFZSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50204276   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50204276(CHEMBL3900985)
Affinity DataIC50:  3.37E+4nMAssay Description:Inhibition of human ERG by electrophysiology methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50204276(CHEMBL3900985)
Affinity DataIC50:  86nMAssay Description:Inhibition of human ROMK expressed in CHO cells after 6 mins at -70 mV holding potential by electrophysiology methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed