BDBM50204411 (3R,4R)-N-hydroxy-4-(4-((2-(trifluoromethyl)quinolin-4-yl)methyl)benzamido)-tetrahydro-2H-pyran-3-carboxamide::CHEMBL234224

SMILES ONC(=O)[C@H]1COCC[C@H]1NC(=O)c1ccc(Cc2cc(nc3ccccc23)C(F)(F)F)cc1

InChI Key InChIKey=RGJDIXGJLGTWJM-AZUAARDMSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50204411   

TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50204411((3R,4R)-N-hydroxy-4-(4-((2-(trifluoromethyl)quinol...)
Affinity DataIC50:  260nMAssay Description:Inhibition of TACE in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Sus scrofa (pig))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50204411((3R,4R)-N-hydroxy-4-(4-((2-(trifluoromethyl)quinol...)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of pig TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed