BDBM50204493 1-(oxazol-2-yl)-7-phenylheptan-1-one::CHEMBL220125

SMILES O=C(CCCCCCc1ccccc1)c1ncco1

InChI Key InChIKey=GWMQJJIAUUBGNE-UHFFFAOYSA-N

Data  5 KI  14 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 19 hits for monomerid = 50204493   

TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50204493(1-(oxazol-2-yl)-7-phenylheptan-1-one | CHEMBL22012...)
Affinity DataKi:  48nMAssay Description:Inhibition of rat recombinant FAAH expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50204493(1-(oxazol-2-yl)-7-phenylheptan-1-one | CHEMBL22012...)
Affinity DataKi:  48nMAssay Description:Inhibition of rat recombinant FAAH expressed in Escherichia coli by [14C]oleamide breakdownMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50204493(1-(oxazol-2-yl)-7-phenylheptan-1-one | CHEMBL22012...)
Affinity DataKi:  48nMAssay Description:Inhibition of FAAHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50204493(1-(oxazol-2-yl)-7-phenylheptan-1-one | CHEMBL22012...)
Affinity DataKi:  48nMAssay Description:Inhibition of FAAHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50204493(1-(oxazol-2-yl)-7-phenylheptan-1-one | CHEMBL22012...)
Affinity DataKi:  48nMAssay Description:Inhibition of rat FAAHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50204493(1-(oxazol-2-yl)-7-phenylheptan-1-one | CHEMBL22012...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of rat recombinant FAAH expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLiver carboxylesterase 1(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50204493(1-(oxazol-2-yl)-7-phenylheptan-1-one | CHEMBL22012...)
Affinity DataIC50:  20nMAssay Description:Inhibition of TGHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLiver carboxylesterase 1(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50204493(1-(oxazol-2-yl)-7-phenylheptan-1-one | CHEMBL22012...)
Affinity DataIC50:  20nMAssay Description:Inhibition of TGHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutral cholesterol ester hydrolase 1(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50204493(1-(oxazol-2-yl)-7-phenylheptan-1-one | CHEMBL22012...)
Affinity DataIC50:  1.90E+4nMAssay Description:Inhibition of KIAA1363More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50204493(1-(oxazol-2-yl)-7-phenylheptan-1-one | CHEMBL22012...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of rat FAAH expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutral cholesterol ester hydrolase 1(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50204493(1-(oxazol-2-yl)-7-phenylheptan-1-one | CHEMBL22012...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of KIAA1363 hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLiver carboxylesterase 1(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50204493(1-(oxazol-2-yl)-7-phenylheptan-1-one | CHEMBL22012...)
Affinity DataIC50:  20nMAssay Description:Inhibition of TGHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50204493(1-(oxazol-2-yl)-7-phenylheptan-1-one | CHEMBL22012...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of rat recombinant FAAH expressed in Escherichia coli by [14C]oleamide breakdownMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutral cholesterol ester hydrolase 1(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50204493(1-(oxazol-2-yl)-7-phenylheptan-1-one | CHEMBL22012...)
Affinity DataIC50:  1.90E+4nMAssay Description:Inhibition of KIAA1363More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50204493(1-(oxazol-2-yl)-7-phenylheptan-1-one | CHEMBL22012...)
Affinity DataIC50:  43nMAssay Description:Inhibition of human FAAHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50204493(1-(oxazol-2-yl)-7-phenylheptan-1-one | CHEMBL22012...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of rat FAAHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLiver carboxylesterase 1(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50204493(1-(oxazol-2-yl)-7-phenylheptan-1-one | CHEMBL22012...)
Affinity DataIC50:  20nMAssay Description:Inhibition of TGH (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol lipase-alpha(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50204493(1-(oxazol-2-yl)-7-phenylheptan-1-one | CHEMBL22012...)
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of full-length human DAGLalpha expressed in HEK293T cell membranes using para-nitrophenylbutyrate by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutral cholesterol ester hydrolase 1(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50204493(1-(oxazol-2-yl)-7-phenylheptan-1-one | CHEMBL22012...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of KIAA1363 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed