BDBM50204861 (6-hydroxy-1H-benzimidazol-2-yl)-[4-(3-methoxy-benzyl)-piperidin-1-yl]-methanone::CHEMBL222665

SMILES COc1cccc(CC2CCN(CC2)C(=O)c2nc3cc(O)c(O)cc3[nH]2)c1

InChI Key InChIKey=JFVFBRUZCXQANP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50204861   

TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50204861((6-hydroxy-1H-benzimidazol-2-yl)-[4-(3-methoxy-ben...)
Affinity DataIC50:  2.5nMAssay Description:Antagonist activity at NR2B NMDA receptor in Wistar rat neocortical cells assessed as inhibition of NMDA-evoked elevation of intracellular calcium co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50204861((6-hydroxy-1H-benzimidazol-2-yl)-[4-(3-methoxy-ben...)
Affinity DataIC50:  3nMAssay Description:Displacement of [3H]Ro 25,6981 from NR2B NMDA receptor in rat forebrainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed