BDBM50204865 CHEMBL220611::[4-(4-fluoro-benzyl)-piperidin-1-yl)]-(6-hydroxy-1H-benzimidazol-2-yl)-methanone
SMILES Oc1cc2nc([nH]c2cc1O)C(=O)N1CCC(Cc2ccc(F)cc2)CC1
InChI Key InChIKey=YNLLMIQTRYSAKL-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50204865
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Gedeon Richter
Curated by ChEMBL
Gedeon Richter
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Antagonist activity at NR2B NMDA receptor in Wistar rat neocortical cells assessed as inhibition of NMDA-evoked elevation of intracellular calcium co...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Gedeon Richter
Curated by ChEMBL
Gedeon Richter
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Displacement of [3H]Ro 25,6981 from NR2B NMDA receptor in rat forebrainMore data for this Ligand-Target Pair