BDBM50205140 CHEMBL3946811

SMILES COc1cc2c(Oc3ccc(NC(=O)c4nn(-c5ccccc5F)c(=O)n4C)cc3F)ccnc2cc1OCCCN1CCN(C)CC1

InChI Key InChIKey=WDAHGVLBPINGHW-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50205140   

TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Key Laboratory Of Structure-Based Drug Design And Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL
LigandPNGBDBM50205140(CHEMBL3946811)
Affinity DataIC50:  95nMAssay Description:Inhibition of PDGFRalpha (unknown origin) after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Key Laboratory Of Structure-Based Drug Design And Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL
LigandPNGBDBM50205140(CHEMBL3946811)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of c-MET (unknown origin) using poly(Glu, Tyr)4:1 as substrate after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Key Laboratory Of Structure-Based Drug Design And Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL
LigandPNGBDBM50205140(CHEMBL3946811)
Affinity DataIC50:  8.20nMAssay Description:Inhibition of FLT3 (unknown origin) after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Key Laboratory Of Structure-Based Drug Design And Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL
LigandPNGBDBM50205140(CHEMBL3946811)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of EGFR (unknown origin) after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Key Laboratory Of Structure-Based Drug Design And Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL
LigandPNGBDBM50205140(CHEMBL3946811)
Affinity DataIC50:  480nMAssay Description:Inhibition of VEGFR2 (unknown origin) after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Key Laboratory Of Structure-Based Drug Design And Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL
LigandPNGBDBM50205140(CHEMBL3946811)
Affinity DataIC50:  3.40nMAssay Description:Inhibition of c-Kit (unknown origin) after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage-stimulating protein receptor(Homo sapiens (Human))
Key Laboratory Of Structure-Based Drug Design And Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL
LigandPNGBDBM50205140(CHEMBL3946811)
Affinity DataIC50:  141nMAssay Description:Inhibition of Ron (unknown origin) after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed