BDBM50205651 4-(3,4-dichlorophenyl)-2-methyl-7-(3-(piperidin-1-yl)propoxy)-1,2,3,4-tetrahydro-2,6-naphthyridine::CHEMBL247683

SMILES CN1CC(c2ccc(Cl)c(Cl)c2)c2cnc(OCCCN3CCCCC3)cc2C1

InChI Key InChIKey=HFOWUCXCCMJFIB-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50205651   

TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50205651(4-(3,4-dichlorophenyl)-2-methyl-7-(3-(piperidin-1-...)
Affinity DataKi:  15nMAssay Description:Binding affinity to rat SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50205651(4-(3,4-dichlorophenyl)-2-methyl-7-(3-(piperidin-1-...)
Affinity DataKi:  18nMAssay Description:Displacement of N-[3H]alpha-methylhistamine from human histamine H3 receptor expressed in SK-N-MC cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50205651(4-(3,4-dichlorophenyl)-2-methyl-7-(3-(piperidin-1-...)
Affinity DataKi:  120nMAssay Description:Binding affinity to human SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed