BDBM50205681 CHEMBL230394::N1-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phenylethyl)-N1-methyl-N3-(4-(methylsulfonamidomethyl)phenyl)malonamide

SMILES CN([C@H](CN1CC[C@H](O)C1)c1ccccc1)C(=O)CC(=O)Nc1ccc(CNS(C)(=O)=O)cc1

InChI Key InChIKey=DAZHRURPDJGCFS-FCHUYYIVSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50205681   

TargetKappa-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50205681(CHEMBL230394 | N1-((S)-2-((S)-3-hydroxypyrrolidin-...)
Affinity DataKi:  96nMAssay Description:Agonist activity at human kappa opioid receptor by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50205681(CHEMBL230394 | N1-((S)-2-((S)-3-hydroxypyrrolidin-...)
Affinity DataIC50:  5.40E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed