BDBM50205705 (2S,3S,4R)-5-((R)-6-amino-2-phenylethynyl-9H-purin-3-yl)-3,4-dihydroxy-tetrahydro-furan-2-carboxylic acid ethylamide::CHEMBL223270

SMILES CCNC(=O)[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)nc(nc12)C#Cc1ccccc1

InChI Key InChIKey=SWXXHYTUMIMRFO-KSVNGYGVSA-N

Data  7 KI  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50205705   

TargetAdenosine receptor A3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50205705((2S,3S,4R)-5-((R)-6-amino-2-phenylethynyl-9H-purin...)
Affinity DataKi:  6.20nMAssay Description:Displacement of [3H]NECA from human recombinant adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50205705((2S,3S,4R)-5-((R)-6-amino-2-phenylethynyl-9H-purin...)
Affinity DataKi:  120nMAssay Description:Displacement of [3H]-CGS- 51680 from Adenosine A2A receptor of rat striatum.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50205705((2S,3S,4R)-5-((R)-6-amino-2-phenylethynyl-9H-purin...)
Affinity DataKi:  120nMAssay Description:Binding affinity against adenosine A2a receptor from rat striatum using [3H]-CGS- 21680 as a radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50205705((2S,3S,4R)-5-((R)-6-amino-2-phenylethynyl-9H-purin...)
Affinity DataKi:  560nMAssay Description:Displacement of [3H]CCPA from human recombinant adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50205705((2S,3S,4R)-5-((R)-6-amino-2-phenylethynyl-9H-purin...)
Affinity DataKi:  620nMAssay Description:Displacement of [3H]NECA from human recombinant adenosine A2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50205705((2S,3S,4R)-5-((R)-6-amino-2-phenylethynyl-9H-purin...)
Affinity DataKi:  698nMAssay Description:Displacement of [3H]CHA from Adenosine A1 receptor of rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50205705((2S,3S,4R)-5-((R)-6-amino-2-phenylethynyl-9H-purin...)
Affinity DataKi:  698nMAssay Description:Binding affinity against adenosine A1 receptor from rat brain using [3H]CHA as a radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50205705((2S,3S,4R)-5-((R)-6-amino-2-phenylethynyl-9H-purin...)
Affinity DataEC50:  1.50E+3nMAssay Description:Functional activity against adenosine A2a receptor from rat aorta.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50205705((2S,3S,4R)-5-((R)-6-amino-2-phenylethynyl-9H-purin...)
Affinity DataEC50: >1nMAssay Description:Vasorelaxation as Adenosine A2A receptor activity in rat aortaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50205705((2S,3S,4R)-5-((R)-6-amino-2-phenylethynyl-9H-purin...)
Affinity DataEC50: >1nMAssay Description:Adenosine A1 receptor mediated negative chronotropic activity in spontaneously beating rat atriaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50205705((2S,3S,4R)-5-((R)-6-amino-2-phenylethynyl-9H-purin...)
Affinity DataEC50: >1.00E+4nMAssay Description:Functional activity against adenosine A1 receptor from rat atria.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed