BDBM50206224 9-(3-(piperidin-1-yl)propoxy)-6-p-tolyl-1,2,3,5,6,10b-hexahydropyrrolo[2,1-a]isoquinoline::CHEMBL240466

SMILES Cc1ccc(cc1)C1CN2CCCC2c2cc(OCCCN3CCCCC3)ccc12

InChI Key InChIKey=SHAFCOFWNARKDQ-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50206224   

TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50206224(9-(3-(piperidin-1-yl)propoxy)-6-p-tolyl-1,2,3,5,6,...)
Affinity DataKi:  2nMAssay Description:Antagonist activity at human histamine H3 receptor expressed in SK-N-MC cells assessed as effect on cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50206224(9-(3-(piperidin-1-yl)propoxy)-6-p-tolyl-1,2,3,5,6,...)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]citalopram from rat brain SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50206224(9-(3-(piperidin-1-yl)propoxy)-6-p-tolyl-1,2,3,5,6,...)
Affinity DataKi:  4.70nMAssay Description:Displacement of N-[3H]-alpha-methylhistamine from human histamine H3 receptor expressed in SK-N-MC cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed