BDBM50206315 CHEMBL2356181

SMILES Nc1sc(cc1C(=O)NCC#C)-c1ccccc1

InChI Key InChIKey=JRXAWCPQHCUZHZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50206315   

TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50206315(CHEMBL2356181)
Affinity DataIC50:  1.86E+4nMAssay Description:Inhibition of human 15-LOX-1 assessed as reduction in conversion of linoleic acid to 13(S)-HpODE incubated for 10 mins followed by linoleic acid addi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed