BDBM50206484 (2R,3S,4R,5R)-2-(5-((E)-2-bromovinyl)-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-hydroxy-5-(hydroxymethyl)-tetrahydrofuran-3-yl decanoate::CHEMBL400618
SMILES CCCCCCCCCC(=O)O[C@H]1[C@H](O)[C@@H](CO)O[C@H]1n1cc(C=CBr)c(=O)[nH]c1=O
InChI Key InChIKey=UJLLAVMKZANACG-PHXBYCTMSA-N
Data 8 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50206484
Affinity DataIC50: 9.70E+4nMAssay Description:Inhibition of human fibroblast mitochondrial TK2 using dCyd substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human fibroblast mitochondrial TK2 using dThd substrateMore data for this Ligand-Target Pair
TargetThymidine kinase(Varicella-zoster virus (strain Dumas) (HHV-3) (Hum...)
University Of Ferrara
Curated by ChEMBL
University Of Ferrara
Curated by ChEMBL
Affinity DataIC50: 8.45E+5nMAssay Description:Inhibition of VZV TK assessed as [methyl-3H]dThd phosphorylationMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human TK1 assessed as [methyl-3H]dThd phosphorylationMore data for this Ligand-Target Pair
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of human TK2 assessed as [methyl-3H]dThd phosphorylationMore data for this Ligand-Target Pair
TargetDeoxyguanosine kinase, mitochondrial(Homo sapiens (Human))
University Of Ferrara
Curated by ChEMBL
University Of Ferrara
Curated by ChEMBL
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human fibroblast mitochondrial deoxyguanosine kinaseMore data for this Ligand-Target Pair
TargetThymidine kinase(Human herpesvirus 1 (strain SC16) (HHV-1) (Human h...)
University Of Ferrara
Curated by ChEMBL
University Of Ferrara
Curated by ChEMBL
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of HSV1 TK assessed as [methyl-3H]dThd phosphorylationMore data for this Ligand-Target Pair
Affinity DataIC50: 1.63E+5nMAssay Description:Inhibition of Drosophila melanogaster dNK assessed as [methyl-3H]dThd phosphorylationMore data for this Ligand-Target Pair