BDBM50206497 1-[2'-O-(4-aminobutanoyl)-beta-D-arabinofuranosyl]-5(E)-(2-bromovinyl)uracil::CHEMBL400233

SMILES NCCCC(=O)O[C@H]1[C@H](O)[C@@H](CO)O[C@H]1n1cc(C=CBr)c(=O)[nH]c1=O

InChI Key InChIKey=IQCSJPCYLWAYFM-SGESHTKJSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50206497   

TargetThymidine kinase 2, mitochondrial(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50206497(1-[2'-O-(4-aminobutanoyl)-beta-D-arabinofuranosyl]...)
Affinity DataIC50:  1.87E+5nMAssay Description:Inhibition of human TK2 assessed as [methyl-3H]dThd phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase, cytosolic(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50206497(1-[2'-O-(4-aminobutanoyl)-beta-D-arabinofuranosyl]...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of human TK1 assessed as [methyl-3H]dThd phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Human herpesvirus 1 (strain SC16) (HHV-1) (Human h...)
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50206497(1-[2'-O-(4-aminobutanoyl)-beta-D-arabinofuranosyl]...)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibition of HSV1 TK assessed as [methyl-3H]dThd phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Varicella-zoster virus (strain Dumas) (HHV-3) (Hum...)
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50206497(1-[2'-O-(4-aminobutanoyl)-beta-D-arabinofuranosyl]...)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of VZV TK assessed as [methyl-3H]dThd phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxynucleoside kinase(Drosophila melanogaster)
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50206497(1-[2'-O-(4-aminobutanoyl)-beta-D-arabinofuranosyl]...)
Affinity DataIC50:  1.60E+5nMAssay Description:Inhibition of Drosophila melanogaster dNK assessed as [methyl-3H]dThd phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed