BDBM50206920 (+/-)-3-O-[4-(4,5-dihydro-5-oxo-1,2,4-4H-oxadiazol-3-yl)phenyl]-2-O-tetradecyl-1-O-triphenylmethylglycerol::CHEMBL373999

SMILES CCCCCCCCCCCCCCOC(COc1ccc(cc1)-c1nc(=O)o[nH]1)COC(c1ccccc1)(c1ccccc1)c1ccccc1

InChI Key InChIKey=GKFYIXXLQZISEA-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50206920   

TargetPhospholipase A2, membrane associated(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50206920((+/-)-3-O-[4-(4,5-dihydro-5-oxo-1,2,4-4H-oxadiazol...)
Affinity DataIC50:  900nMAssay Description:Inhibition of human group IIA PLA2 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50206920((+/-)-3-O-[4-(4,5-dihydro-5-oxo-1,2,4-4H-oxadiazol...)
Affinity DataIC50:  5.75E+3nMAssay Description:Inhibition of human group IB PLA2 in [3H]oleate-labeled Escherichia coli membrane by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2, membrane associated(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50206920((+/-)-3-O-[4-(4,5-dihydro-5-oxo-1,2,4-4H-oxadiazol...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of human group IIA PLA2 in [3H]oleate-labeled Escherichia coli membrane by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2, major isoenzyme(Sus scrofa (pig))
Université

Curated by ChEMBL
LigandPNGBDBM50206920((+/-)-3-O-[4-(4,5-dihydro-5-oxo-1,2,4-4H-oxadiazol...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of pig group IB PLA2 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGroup 10 secretory phospholipase A2(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50206920((+/-)-3-O-[4-(4,5-dihydro-5-oxo-1,2,4-4H-oxadiazol...)
Affinity DataIC50:  1.25E+3nMAssay Description:Inhibition of human group X PLA2 in [3H]oleate-labeled Escherichia coli membrane by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2 group V(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50206920((+/-)-3-O-[4-(4,5-dihydro-5-oxo-1,2,4-4H-oxadiazol...)
Affinity DataIC50:  660nMAssay Description:Inhibition of human group V PLA2 in [3H]oleate-labeled Escherichia coli membrane by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed