BDBM50207061 CHEMBL3980898

SMILES CO[C@H]1C[C@@H](C1)Oc1cc(F)c(F)c(n1)-c1ccc2O[C@@H](CCC(O)=O)CCc2c1

InChI Key InChIKey=PGPQNVUVHSSUSY-BZUAXINKSA-N

Data  5 IC50  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50207061   

TargetCytochrome P450 3A4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50207061(CHEMBL3980898)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50207061(CHEMBL3980898)
Affinity DataEC50:  24nMAssay Description:Agonist activity at human GPR120 short isoform expressed in CHOK1 cells assessed as beta-arrestin recruitment after 90 mins by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50207061(CHEMBL3980898)
Affinity DataEC50:  35nMAssay Description:Agonist activity at human GPR120 short isoform expressed in CHOK1 cells assessed as increase in IP1 accumulation after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50207061(CHEMBL3980898)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50207061(CHEMBL3980898)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human GPR40 expressed in HEK293 cells assessed as increase in IP1 accumulation after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Mus musculus)
Merck

Curated by ChEMBL
LigandPNGBDBM50207061(CHEMBL3980898)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at mouse GPR40 assessed as increase in IP1 accumulation after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50207061(CHEMBL3980898)
Affinity DataIC50:  2.70E+4nMAssay Description:Inhibition of Nav1.5 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50207061(CHEMBL3980898)
Affinity DataIC50:  2.80E+4nMAssay Description:Inhibition of Cav1.2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 4(Mus musculus)
Merck

Curated by ChEMBL
LigandPNGBDBM50207061(CHEMBL3980898)
Affinity DataEC50:  6.80nMAssay Description:Agonist activity at mouse GPR120 expressed in human U2OS cells assessed as beta-arrestin recruitment after 90 mins by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50207061(CHEMBL3980898)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 4(Mus musculus)
Merck

Curated by ChEMBL
LigandPNGBDBM50207061(CHEMBL3980898)
Affinity DataEC50:  6.40nMAssay Description:Agonist activity at mouse GPR120 expressed in CHOK1 cells assessed as increase in IP1 accumulation after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed