BDBM50207484 1-(4-(3-amino-1H-indazol-4-yl)phenyl)-3-o-tolylurea::CHEMBL376077::N-[4-(3-amino-1H-indazol-4-yl)phenyl]-N'-(2-methylphenyl)-urea

SMILES Cc1ccccc1NC(=O)Nc1ccc(cc1)-c1cccc2[nH]nc(N)c12

InChI Key InChIKey=XTKIFGMBONJHTF-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50207484   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207484(1-(4-(3-amino-1H-indazol-4-yl)phenyl)-3-o-tolylure...)
Affinity DataIC50:  80nMAssay Description:Inhibition of VEGF-induced human KDR phosphorylation in mouse 3T3 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207484(1-(4-(3-amino-1H-indazol-4-yl)phenyl)-3-o-tolylure...)
Affinity DataIC50:  87nMAssay Description:Inhibition of VEGF-induced human KDR phosphorylation in mouse 3T3 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50207484(1-(4-(3-amino-1H-indazol-4-yl)phenyl)-3-o-tolylure...)
Affinity DataIC50:  86nMAssay Description:Inhibition of c-Kit by HTRF methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207484(1-(4-(3-amino-1H-indazol-4-yl)phenyl)-3-o-tolylure...)
Affinity DataIC50:  3nMAssay Description:Inhibition of FLT3 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50207484(1-(4-(3-amino-1H-indazol-4-yl)phenyl)-3-o-tolylure...)
Affinity DataIC50:  86nMAssay Description:Inhibition of c-Kit by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed