BDBM50207594 2,3-Dihydroxy-6-nitro-benzo[f]quinoxaline-7-sulfonic acid amide::2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo(f)quinoxaline::2,3-dihydroxy-6-nitro-7-sulfamoylbenzo(f)quinoxaline::3-Hydroxy-6-nitro-7-sulfamoyl-benzo[f]quinoxalin-2-ol anion::6-Nitro-2,3-dioxo-1,2,3,4,4a,10b-hexahydro-benzo[f]quinoxaline-7-sulfonic acid amide::6-Nitro-2,3-dioxo-1,2,3,4-tetrahydro-benzo[f]quinoxaline-7-sulfinic acid amide::6-Nitro-2,3-dioxo-1,2,3,4-tetrahydro-benzo[f]quinoxaline-7-sulfonic acid amide::6-Nitro-2,3-dioxo-2,3-dihydro-benzo[f]quinoxaline-7-sulfonic acid amide::6-nitro-2,3-dioxo-1,2,3,4-tetrahydrobenzo[f]quinoxaline-7-sulfonamide::CHEMBL222519
SMILES NS(=O)(=O)c1cccc2c1c(cc1[nH]c(=O)c(=O)[nH]c21)[N+]([O-])=O
InChI Key InChIKey=UQNAFPHGVPVTAL-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 28 hits for monomerid = 50207594
Affinity DataKi: 210nMAssay Description:Inhibition of [3H]-AMPA binding to human GluR2 receptors expressed in HEK 293 cellsMore data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataKi: 260nMAssay Description:Ability to displace binding of [3H]AMPA to recombinant human Ionotropic glutamate receptor AMPA 2More data for this Ligand-Target Pair
Affinity DataKi: 600nMAssay Description:Ability to displace binding of [3H]AMPA to recombinant human Ionotropic glutamate receptor AMPA 4More data for this Ligand-Target Pair
Affinity DataKi: 900nMAssay Description:Ability to displace binding of [3H]AMPA to recombinant human Ionotropic glutamate receptor AMPA 3More data for this Ligand-Target Pair
Affinity DataKi: 1.60E+3nMAssay Description:Ability to displace binding of [3H]AMPA to recombinant human Ionotropic glutamate receptor AMPA 1More data for this Ligand-Target Pair
Affinity DataKi: 1.17E+4nMAssay Description:Inhibition of [3H]-KA binding to iontropic glutamate receptor 5More data for this Ligand-Target Pair
Affinity DataKi: 1.32E+4nMAssay Description:Ability to displace binding of [3H]AMPA to recombinant human AMPA receptor Ionotropic glutamate receptor ionotropic kainate 2More data for this Ligand-Target Pair
Affinity DataKi: 1.32E+4nMAssay Description:Inhibition of [3H]-KA binding to iontropic glutamate receptor 6More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, kainate 3(Homo sapiens (Human))
University Walk
Curated by ChEMBL
University Walk
Curated by ChEMBL
Affinity DataKi: 1.80E+4nMAssay Description:Displacement of [3H]kainate from human GLUK7 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 3.30E+4nMAssay Description:Compound was tested for binding affinity against glycine site of NMDA receptor using [3H]-glycine as a radioligand.More data for this Ligand-Target Pair
Affinity DataKi: 3.30E+4nMAssay Description:Ability of the compound to displace [3H]-glycine from NMDA receptorMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity of the compound towards glycine binding site on NMDA receptor was determined in rat whole brain membrane using strychnine-insensitiv...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+5nMAssay Description:Ability to displace binding of [3H]KA to recombinant human KA receptor Ionotropic glutamate receptor ionotropic kainate 2 expressed in EK 293 cell me...More data for this Ligand-Target Pair
Affinity DataIC50: 3.70E+4nMAssay Description:Inhibition of glutamate-induced calcium influx in HEK293 cells expressing human GLUK5 by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of glutamate-induced calcium influx in HEK293 cells expressing human GLUA2More data for this Ligand-Target Pair
Affinity DataIC50: 3.70E+4nMAssay Description:Antagonist activity at human recombinant GLUK5 receptor expressed in HEK293 cells assessed as inhibition of glutamate-stimulated calcium influx by FL...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of glutamate-induced calcium influx in HEK293 cells expressing human GLUA4More data for this Ligand-Target Pair
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of glutamate-induced calcium influx in HEK293 cells expressing human GLUA1More data for this Ligand-Target Pair
Affinity DataKd: 1.78E+3nMAssay Description:Antagonist activity against GLUK5-containing kainate receptor by inhibition of kainate-induced depolarization of neonatal rat dorsal root fibersMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of glutamate-induced calcium influx in HEK293 cells expressing human GLUA3More data for this Ligand-Target Pair
Affinity DataIC50: 7.40E+4nMAssay Description:Antagonist activity at human recombinant GluR6 expressed in HEK cells coexpressing aequorine assessed as inhibition of glutamate-induced Ca2+ influx ...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, kainate 3(Homo sapiens (Human))
University Walk
Curated by ChEMBL
University Walk
Curated by ChEMBL
Affinity DataIC50: 4.40E+4nMAssay Description:Displacement of [3H]kainate from human GLUK7 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Affinity for N-methyl-D-aspartate glutamate receptor 1 in rat brain synaptic membranes, using [3H]glycine as radioligandMore data for this Ligand-Target Pair
Affinity DataKd: 1.78E+3nMAssay Description:Antagonism on GLUK5 containing kainate induced deploarization of isolated neonatal rat dorsal root C-fibersMore data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+3nMAssay Description:Antagonist activity at human recombinant GLUA2-AMPA receptor expressed in HEK293 cells assessed as inhibition of glutamate-stimulated calcium influx ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.90E+4nMAssay Description:Antagonist activity at human recombinant GLUK6 expressed in HEK293 cells assessed as inhibition of glutamate-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of glutamate-induced calcium influx in HEK293 cells expressing human GLUK6More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Affinity for N-methyl-D-aspartate glutamate receptor 1 in rat brain synaptic membranes, using [3H]glycine as radioligandMore data for this Ligand-Target Pair