BDBM50208176 CHEMBL3976777

SMILES Nc1ncnc(N2CCC[C@H]2c2nn3cccc3c(=O)n2-c2ccccc2)c1C#N

InChI Key InChIKey=QOGPJIWCEKLLOE-INIZCTEOSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50208176   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50208176(CHEMBL3976777)
Affinity DataIC50:  6.60nMAssay Description:Inhibition of PI3Kdelta in human THP1 cells assessed as reduction in MCSF-stimulated akt phosphorylation at Thr308 preincubated for 30 mins followed ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50208176(CHEMBL3976777)
Affinity DataIC50:  4.60nMAssay Description:Inhibition of full length recombinant human N-terminal His6-tagged PI3K p110delta/human p85alpha expressed in baculovirus infected sf21 cells using P...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed