BDBM50208689 (R)-N-(1-(5-(2-(1H-indol-3-yl)ethyl)-4-(3-methoxybenzyl)-4H-1,2,4-triazol-3-yl)-2-(1H-indol-3-yl)ethyl)-2-amino-2-methylpropanamide::CHEMBL376258

SMILES COc1cccc(Cn2c(CCc3c[nH]c4ccccc34)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)C(C)(C)N)c1

InChI Key InChIKey=IFOQRGBXSMPXLY-SSEXGKCCSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50208689   

TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM50208689((R)-N-(1-(5-(2-(1H-indol-3-yl)ethyl)-4-(3-methoxyb...)
Affinity DataIC50:  18nMAssay Description:Displacement of [125I-His9]ghrelin from human GHS1a receptor expressed in LLC PK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM50208689((R)-N-(1-(5-(2-(1H-indol-3-yl)ethyl)-4-(3-methoxyb...)
Affinity DataIC50:  18nMAssay Description:Displacement of 125I-His9-ghrelin from human GHSR1a expressed in LLCPK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM50208689((R)-N-(1-(5-(2-(1H-indol-3-yl)ethyl)-4-(3-methoxyb...)
Affinity DataEC50:  4nMAssay Description:Agonist activity at GHSR1a expressed in CHO cells assessed as accumulation of intracellular calcium levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM50208689((R)-N-(1-(5-(2-(1H-indol-3-yl)ethyl)-4-(3-methoxyb...)
Affinity DataEC50:  4nMAssay Description:Agonist activity at human GHS1a receptor expressed in CHO cells assessed as induction of intracellular calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed