BDBM50208748 (4-(((S)-3-((dimethylamino)methyl)pyrrolidin-1-yl)methyl)-3-(trifluoromethyl)phenyl)(4-methyl-3-(4-(pyrimidin-5-yl)pyrimidin-2-ylamino)phenylamino)methanol hydrochloride::CHEMBL538337

SMILES CN(C)C[C@@H]1CCN(Cc2ccc(cc2C(F)(F)F)C(O)Nc2ccc(C)c(Nc3nccc(n3)-c3cncnc3)c2)C1

InChI Key InChIKey=UIQVTQZGYNQWLN-TYKNXJODSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50208748   

TargetTyrosine-protein kinase Lyn(Homo sapiens (Human))
Nippon Shinyaku

Curated by ChEMBL
LigandPNGBDBM50208748((4-(((S)-3-((dimethylamino)methyl)pyrrolidin-1-yl)...)
Affinity DataIC50:  7.60nMAssay Description:Inhibition of human Lyn kinase expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Nippon Shinyaku

Curated by ChEMBL
LigandPNGBDBM50208748((4-(((S)-3-((dimethylamino)methyl)pyrrolidin-1-yl)...)
Affinity DataIC50:  32nMAssay Description:Inhibition of human Abl kinase expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed