BDBM50209663 CHEMBL374384::MRS-2670::diphosphoric acid 1-alpha-D-glucopyranosyl ester 2-((4'-thio)uridin-5''-yl) ester

SMILES OC[C@H]1O[C@H](OP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2ccc(=S)[nH]c2=O)[C@H](O)[C@@H](O)[C@@H]1O

InChI Key InChIKey=UZCPXQNAFYGUOP-JZMIEXBBSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50209663   

TargetP2Y purinoceptor 14(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50209663(CHEMBL374384 | MRS-2670 | diphosphoric acid 1-alph...)
Affinity DataEC50:  350nMAssay Description:Agonist activity at human P2Y14 expressed in COS7 cells assessed as stimulation of PLC-mediated [3H]inositol hydrolsisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 6(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50209663(CHEMBL374384 | MRS-2670 | diphosphoric acid 1-alph...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human P2Y6 receptor expressed in human 1321N1 cells coexpressing phospholipase C-activating Gq protein assessed as [3H]inositol p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 14(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50209663(CHEMBL374384 | MRS-2670 | diphosphoric acid 1-alph...)
Affinity DataEC50:  11nMAssay Description:Agonist activity at human P2Y14 receptor expressed in HEK293 cells coexpressing phospholipase C-activating Gi protein cells assessed as inhibition of...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 14(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50209663(CHEMBL374384 | MRS-2670 | diphosphoric acid 1-alph...)
Affinity DataEC50:  290nMAssay Description:Agonist activity at human P2Y14 receptor expressed in human COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed