BDBM50210079 (R)-2-[8-(2-methoxy-ethoxymethyl)-2,3,6,7-tetrahydro-benzo[1,2-b;4,5-b']difuran-4-yl]-1-methyl-ethylamine::CHEMBL397321

SMILES COCCOCc1c2CCOc2c(C[C@@H](C)N)c2CCOc12

InChI Key InChIKey=LSJOUYHVPXKFHU-LLVKDONJSA-N

Data  1 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50210079   

Target5-hydroxytryptamine receptor 2B(RAT)
Alcon Research

Curated by ChEMBL
LigandPNGBDBM50210079((R)-2-[8-(2-methoxy-ethoxymethyl)-2,3,6,7-tetrahyd...)
Affinity DataEC50:  5.80nMAssay Description:Agonist activity at 5HT2B receptor in rat stomach fundus assessed as intracellular calcium mobilization relative to 5HTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Alcon Research

Curated by ChEMBL
LigandPNGBDBM50210079((R)-2-[8-(2-methoxy-ethoxymethyl)-2,3,6,7-tetrahyd...)
Affinity DataEC50:  8.60nMAssay Description:Agonist activity at 5HT2C receptor expressed in rat SR3T3 cells assessed as intracellular calcium mobilization relative to 5HTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Alcon Research

Curated by ChEMBL
LigandPNGBDBM50210079((R)-2-[8-(2-methoxy-ethoxymethyl)-2,3,6,7-tetrahyd...)
Affinity DataIC50:  0.880nMAssay Description:Displacement of [125I]DOI from 5HT2A receptor in rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Alcon Research

Curated by ChEMBL
LigandPNGBDBM50210079((R)-2-[8-(2-methoxy-ethoxymethyl)-2,3,6,7-tetrahyd...)
Affinity DataEC50:  71nMAssay Description:Agonist activity at 5HT2A receptor in rat A7r5 cells assessed as intracellular calcium mobilization relative to 5HTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed