BDBM50210361 CHEMBL234097::N-(2-((4-cyano-4-(2-(trifluoromethyl)phenyl)cyclohexyl)methylamino)pyridin-3-yl)isoxazole-5-carboxamide

SMILES FC(F)(F)c1ccccc1C1(CCC(CNc2ncccc2NC(=O)c2ccno2)CC1)C#N

InChI Key InChIKey=GNNDELPJNRLQIM-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50210361   

TargetB1 bradykinin receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50210361(CHEMBL234097 | N-(2-((4-cyano-4-(2-(trifluoromethy...)
Affinity DataKi:  0.600nMAssay Description:Binding affinity at human bradykinin B1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50210361(CHEMBL234097 | N-(2-((4-cyano-4-(2-(trifluoromethy...)
Affinity DataIC50:  0.450nMAssay Description:Antagonist activity in human bradykinin B1 receptor by FLIPR methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed