BDBM50211367 Ac-Nle4-cyclo(Asp5-His6-D-Phe(4-Cl)-Pro8-Trp9-Lys10)-NH2::CHEMBL376339
SMILES CCCC[C@H](NC(C)=O)C(=O)N[C@H]1CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc2cc3ccccc3[nH]2)NC(=O)[C@@H]2CCCN2C(=O)[C@@H](Cc2ccc(Cl)cc2)NC(=O)[C@H](Cc2cnc[nH]2)NC1=O)C(N)=O
InChI Key InChIKey=HROUSAHWAGUIEV-CQPWUTEUSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50211367
Affinity DataIC50: >2.00E+4nMAssay Description:Displacement of [125I]NDPalphaMSH from human cloned MC3R expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 82nMAssay Description:Agonist activity at human MC5R expressed in CHO cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataEC50: >5.00E+3nMAssay Description:Agonist activity at human MC3R expressed in CHO cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataIC50: 4.50E+3nMAssay Description:Displacement of [125I]NDPalphaMSH from human cloned MC4R expressed in CHO cellsMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataEC50: 63nMAssay Description:Agonist activity at human melanocortin receptor 1b expressed in CHO cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:Displacement of [125I]NDPalphaMSH from human cloned MC5R expressed in CHO cellsMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 560nMAssay Description:Displacement of [125I]NDPalphaMSH from human cloned melanocortin receptor 1b expressed in CHO cellsMore data for this Ligand-Target Pair