BDBM50211394 Ac-Nle4-cyclo(Asp5-His6-L-Phe-Pro8-Trp9-Lys10)-NH2::CHEMBL375947
SMILES CCCC[C@H](NC(C)=O)C(=O)N[C@H]1CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc2cc3ccccc3[nH]2)NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC1=O)C(N)=O
InChI Key InChIKey=DKOABVBSZAEDPP-IFLLZMBLSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50211394
Affinity DataEC50: 2.00E+3nMAssay Description:Agonist activity at human MC5R expressed in CHO cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataEC50: >1.00E+3nMAssay Description:Agonist activity at human melanocortin receptor 1b expressed in CHO cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+3nMAssay Description:Displacement of [125I]NDPalphaMSH from human cloned MC4R expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 390nMAssay Description:Displacement of [125I]NDPalphaMSH from human cloned MC5R expressed in CHO cellsMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 980nMAssay Description:Displacement of [125I]NDPalphaMSH from human cloned melanocortin receptor 1b expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 860nMAssay Description:Displacement of [125I]NDPalphaMSH from human cloned MC3R expressed in CHO cellsMore data for this Ligand-Target Pair