BDBM50211535 CHEMBL387993::N-((3S,4R)-6-((S)-2-((2,6-dimethylphenylamino)methyl)pyrrolidine-1-carbonyl)-3-hydroxy-2,2-dimethyl-3,4-dihydro-2H-chromen-4-yl)-4-ethylbenzenesulfonamide::rac-trans-N-(6-((S)-2-((2,6-dimethylphenylamino)methyl)pyrrolidine-1-carbonyl)-3-hydroxy-2,2-dimethyl-3,4-dihydro-2H-chromen-4-yl)-4-ethylbenzenesulfonamide

SMILES CCc1ccc(cc1)S(=O)(=O)N[C@H]1[C@H](O)C(C)(C)Oc2ccc(cc12)C(=O)N1CCC[C@H]1CNc1c(C)cccc1C

InChI Key InChIKey=ZGNURVKJDROBKC-RVQNBHMFSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50211535   

TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50211535(CHEMBL387993 | N-((3S,4R)-6-((S)-2-((2,6-dimethylp...)
Affinity DataIC50:  60nMAssay Description:Inhibition of human Kv1.5 channel expressed in mouse L929 cells assessed as blockade of ultra rapidly activating potassium current by volatge clamp t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50211535(CHEMBL387993 | N-((3S,4R)-6-((S)-2-((2,6-dimethylp...)
Affinity DataIC50:  120nMAssay Description:Inhibition of human Kv1.5 channel expressed in mouse L929 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed