BDBM50211844 2-(3-chlorophenylamino)-4-trifluoromethylpyrimidine-5-carboxylic acid N-(tetrahydropyran-4-ylmethyl)amide::CHEMBL226385

SMILES FC(F)(F)c1nc(Nc2cccc(Cl)c2)ncc1C(=O)NCC1CCOCC1

InChI Key InChIKey=BIFWAJIKBGURHJ-UHFFFAOYSA-N

Data  5 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50211844   

TargetCytochrome P450 3A4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50211844(2-(3-chlorophenylamino)-4-trifluoromethylpyrimidin...)
Affinity DataIC50:  5.10E+4nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50211844(2-(3-chlorophenylamino)-4-trifluoromethylpyrimidin...)
Affinity DataEC50:  50nMAssay Description:Agonist activity at human recombinant CB2 receptor expressed in Saccharomyces cerevisiae cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50211844(2-(3-chlorophenylamino)-4-trifluoromethylpyrimidin...)
Affinity DataIC50:  5.10E+4nMAssay Description:Inhibition of human CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50211844(2-(3-chlorophenylamino)-4-trifluoromethylpyrimidin...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50211844(2-(3-chlorophenylamino)-4-trifluoromethylpyrimidin...)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of human CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50211844(2-(3-chlorophenylamino)-4-trifluoromethylpyrimidin...)
Affinity DataIC50:  5.60E+4nMAssay Description:Inhibition of human CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed