BDBM50211972 CHEMBL233823::N-(3-chloro-4-(trifluoromethyl)phenyl)-1-(2-(pyridin-4-yl)ethyl)-1H-pyrazole-5-carboxamide
SMILES FC(F)(F)c1ccc(NC(=O)c2ccnn2CCc2ccncc2)cc1Cl
InChI Key InChIKey=LMEHSVKTVLMKTO-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50211972
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chemical Diversity
Curated by ChEMBL
Chemical Diversity
Curated by ChEMBL
Affinity DataKi: 160nMAssay Description:Displacement of [32P]ATP from human VEGFR2 after 45 minsMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chemical Diversity
Curated by ChEMBL
Chemical Diversity
Curated by ChEMBL
Affinity DataKi: 170nMAssay Description:Inhibition of VEGFR2 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assayMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Chemical Diversity
Curated by ChEMBL
Chemical Diversity
Curated by ChEMBL
Affinity DataIC50: 980nMAssay Description:Inhibition of VEGFR1 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assayMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chemical Diversity
Curated by ChEMBL
Chemical Diversity
Curated by ChEMBL
Affinity DataIC50: 95nMAssay Description:Inhibition of VEGFR2 assessed as inhibition of phosphorylation in human 293 cells by cell-based ELISAMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chemical Diversity
Curated by ChEMBL
Chemical Diversity
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Inhibition of VEGFR2 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assayMore data for this Ligand-Target Pair