BDBM50213115 (R,R)-(-)-5-{1-hydroxy-2-[1-methyl-2-(1-naphthyl)ethylamino]ethyl}-1,3-benzenediol::CHEMBL229401::US10617654, Compound (R,R)-5::US9492405, (R,R)-5::US9492405, 39

SMILES C[C@H](Cc1cccc2ccccc12)NC[C@H](O)c1cc(O)cc(O)c1

InChI Key InChIKey=QGUPDXLZKDANGO-SZNDQCEHSA-N

Data  6 KI  2 IC50  2 Kd  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50213115   

TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
The Usa, As Represented By The Secretary, Department of Health and Human Services

US Patent
LigandPNGBDBM50213115((R,R)-(-)-5-{1-hydroxy-2-[1-methyl-2-(1-naphthyl)e...)
Affinity DataKi:  2.41E+5nMAssay Description:HEK 293 cells stability transfected with cDNA encoding human β2-AR (provided by Dr. Brian Kobilka, Stanford Medical Center, Palo Alto, Calif.) w...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-1 adrenergic receptor(Mus musculus)
The Usa, As Represented By The Secretary, Department of Health and Human Services

US Patent
LigandPNGBDBM50213115((R,R)-(-)-5-{1-hydroxy-2-[1-methyl-2-(1-naphthyl)e...)
Affinity DataKi:  3.35E+6nMAssay Description:β1-AR binding was done on rat cortical membrane following a previously described procedure (Beer et al., Biochem. Pharmacol. 37: 1145-1151, 1988...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
The Usa, As Represented By The Secretary, Department of Health and Human Services

US Patent
LigandPNGBDBM50213115((R,R)-(-)-5-{1-hydroxy-2-[1-methyl-2-(1-naphthyl)e...)
Affinity DataKd:  240nMAssay Description:HEK 293 cells stability transfected with cDNA encoding human β2-AR (provided by Dr. Brian Kobilka, Stanford Medical Center, Palo Alto, Calif.) w...More data for this Ligand-Target Pair
In DepthDetails US Patent