BDBM50213335 CHEMBL60985

SMILES COc1ccc(\C=C2/C(=O)Nc3ccccc23)cc1OC1CC2CCC1C2

InChI Key InChIKey=CCQPFCCZWSBRTL-WQRHYEAKSA-N

Data  3 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50213335   

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))TBA

LigandBDBM50213335(CHEMBL60985)Copy SMILESCopy InChI

Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of Phosphodiesterase 3 (PDE III) at 100 uMMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathway
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails
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TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))TBA

LigandBDBM50213335(CHEMBL60985)Copy SMILESCopy InChI

Affinity DataIC50:  3.70E+3nMAssay Description:Inhibition of Phosphodiesterase 4More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaantibodypediaantibodypediaantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails
Copy BDB DOI

TargetPhosphodiesterase/cAMP-specific 3',5'-cyclic phosphodiesterase 4A/cAMP-specific 3',5'-cyclic phosphodiesterase 4C/cAMP-specific 3',5'-cyclic phosphodiesterase 4D(Mus musculus)TBA

LigandBDBM50213335(CHEMBL60985)Copy SMILESCopy InChI

Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of [3H]rolipram binding to Phosphodiesterase 4 (PDE IV)More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails
Copy BDB DOI