BDBM50213845 CHEMBL14557

SMILES OC(=O)c1cc(NC(=O)[C@H](Cc2ccccc2)NC(=O)c2cc3cc[nH]c3cc2C(=O)NCC23CC4CC(CC(C4)C2)C3)cc(c1)C(O)=O

InChI Key InChIKey=DKYQJTXTKSMTHK-FGLZHOHTSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50213845   

TargetGastrin/cholecystokinin type B receptor(MOUSE)
James Black Foundation

Curated by ChEMBL
LigandPNGBDBM50213845(CHEMBL14557)
Affinity DataKi:  1nMAssay Description:Inhibition of 20 pM [125I]BH-CCK-8S binding to mouse cortical membrane Cholecystokinin 2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(MOUSE)
James Black Foundation

Curated by ChEMBL
LigandPNGBDBM50213845(CHEMBL14557)
Affinity DataKi:  1.10nMAssay Description:Displacement of binding of [125I]CCK-8S to Cholecystokinin type B receptor in mouse cerebral cortex homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(MOUSE)
James Black Foundation

Curated by ChEMBL
LigandPNGBDBM50213845(CHEMBL14557)
Affinity DataKi:  1.10nMAssay Description:In vitro inhibitory activity against Cholecystokinin type B receptor using [125I]BH-CCK-8S as radioligand in mouse cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50213845(CHEMBL14557)
Affinity DataKi:  23nMAssay Description:Compound was tested for binding affinity against Cholecystokinin type B receptor in rat cortical membranes using L-365260 as the radioligand.More data for this Ligand-Target Pair
In DepthDetails
TargetCholecystokinin receptor type A(Cavia porcellus)
James Black Foundation

Curated by ChEMBL
LigandPNGBDBM50213845(CHEMBL14557)
Affinity DataKi:  3.63E+3nMAssay Description:In vitro inhibitory activity against Cholecystokinin type A receptor using [125I]BH-CCK-8S as radioligand in guinea pig pancreatic cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(Cavia porcellus)
James Black Foundation

Curated by ChEMBL
LigandPNGBDBM50213845(CHEMBL14557)
Affinity DataKi:  3.98E+3nMAssay Description:Displacement of [125I]BH-CCK-8S from CC1 receptor expressed in guinea pig pancreatic cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(Cavia porcellus)
James Black Foundation

Curated by ChEMBL
LigandPNGBDBM50213845(CHEMBL14557)
Affinity DataKi:  3.98E+3nMAssay Description:Inhibition of 20 pM [125I]BH-CCK-8S binding to guinea pig pancreas membrane Cholecystokinin 1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed