BDBM50214542 (S)-4-methyl-2-[(S)-2,2,2-trifluoro-1-(4'-methanesulfonyl-biphenyl-4-yl)-ethylamino]-pentanoic acid ((S)-benzyl-cyano-methyl)-amide::CHEMBL399361
SMILES CC(C)C[C@H](N[C@@H](c1ccc(cc1)-c1ccc(cc1)S(C)(=O)=O)C(F)(F)F)C(=O)N[C@@H](Cc1ccccc1)C#N
InChI Key InChIKey=LLEYFYXOCVQUBI-MYKRZTLLSA-N
Data 9 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50214542
TargetCathepsin K(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Inhibition of humanized rabbit cathepsin KMore data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Inhibition of human Cat F expressed in rabbit HIG82 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 117nMAssay Description:Inhibition of human Cat LMore data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Inhibition of trypanosoma cruzi CruzipainMore data for this Ligand-Target Pair
TargetCathepsin K(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Inhibition of humanized rabbit cathepsin KMore data for this Ligand-Target Pair
Affinity DataIC50: 67nMAssay Description:Inhibition of cathepsin LMore data for this Ligand-Target Pair
TargetCathepsin S(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 38nMAssay Description:Inhibition of cathepsin SMore data for this Ligand-Target Pair
TargetCathepsin B(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 953nMAssay Description:Inhibition of cathepsin BMore data for this Ligand-Target Pair
TargetCathepsin B(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 163nMAssay Description:Inhibition of human Cat B in HepG2 cellsMore data for this Ligand-Target Pair