BDBM50214685 1-[(R)-2-{4-[2-((S)-1-amino-3-methylbutyl)-4-trifluoromethylphenyl]-piperazin-1-yl}-1-(4-dichlorobenzyl)-2-oxoethyl]pyrrolidin-2-one::CHEMBL439560
SMILES CC(C)C[C@H](N)c1cc(ccc1N1CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1)N1CCCC1=O)C(F)(F)F
InChI Key InChIKey=GWQJQMUYAJRYAV-AZGAKELHSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50214685
Affinity DataKi: 5.5nMAssay Description:Binding affinity to C57BL/6J mouse MC4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 9.10nMAssay Description:Binding affinity to rat MC4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Displacement of [125I]NDP-MSH from MC4R receptor in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 990nMAssay Description:Displacement of [125I]NDP-MSH from MC5R receptor in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.80E+3nMAssay Description:Displacement of [125I]NDP-MSH from MC3R receptor in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 510nMAssay Description:Agonist activity at human MC4 receptor in HEK293 cells assesed as inhibition of alpha-MSH stimulated cAMP productionMore data for this Ligand-Target Pair
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataEC50: 4.10E+3nMAssay Description:Agonist activity at ghrelin receptorMore data for this Ligand-Target Pair