BDBM50214686 1-((R)-1-(4-(2-((S)-1-amino-3-methylbutyl)-4-fluorophenyl)piperazin-1-yl)-3-(2,4-dichlorophenyl)-1-oxopropan-2-yl)pyrrolidin-2-one::1-[(R)-2-{4-[2-((S)-1-amino-3-methylbutyl)-4-fluorophenyl]piperazin-1-yl}-1-(2,4-dichlorobenzyl)-2-oxoethyl]pyrrolidin-2-one::CHEMBL236732

SMILES CC(C)C[C@H](N)c1cc(F)ccc1N1CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1Cl)N1CCCC1=O

InChI Key InChIKey=NUALMFMLNXDIHK-AZGAKELHSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50214686   

TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50214686(1-((R)-1-(4-(2-((S)-1-amino-3-methylbutyl)-4-fluor...)
Affinity DataKi:  26nMAssay Description:Displacement of [125I]NDP-MSH from MC4R receptor in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50214686(1-((R)-1-(4-(2-((S)-1-amino-3-methylbutyl)-4-fluor...)
Affinity DataKi:  26nMAssay Description:Binding affinity at human MC4RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50214686(1-((R)-1-(4-(2-((S)-1-amino-3-methylbutyl)-4-fluor...)
Affinity DataIC50:  220nMAssay Description:Inhibition of microsomal CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed