BDBM50215431 CHEMBL243319::N-((3-aminobenzo[d]isothiazol-6-yl)methyl)-2-(6-(3-aminophenyl)-5-chloro-3-(cyclobutylamino)-2-oxopyrazin-1(2H)-yl)acetamide

SMILES Nc1nsc2cc(CNC(=O)Cn3c(c(Cl)nc(NC4CCC4)c3=O)-c3cccc(N)c3)ccc12

InChI Key InChIKey=MUPFANVTHIEROV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50215431   

TargetCoagulation factor X(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215431(CHEMBL243319 | N-((3-aminobenzo[d]isothiazol-6-yl)...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215431(CHEMBL243319 | N-((3-aminobenzo[d]isothiazol-6-yl)...)
Affinity DataIC50:  2.68E+4nMAssay Description:Inhibition of factor 7aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215431(CHEMBL243319 | N-((3-aminobenzo[d]isothiazol-6-yl)...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of factor 2aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed